Products

Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC

Hanhua Chemical

Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC
Specifications

HS Code

136215

Appearance White to yellowish - white powder or granule
Solubility Soluble in water, forming a clear viscous solution
Viscosity Can have different viscosity grades (e.g., low, medium, high)
Ph Range 6.5 - 8.5 in 1% aqueous solution
Water Holding Capacity High, can retain a large amount of water
Stability Stable in neutral and slightly alkaline media
Film Forming Property Capable of forming strong and flexible films
Thickening Property Effective thickener in various systems
Emulsifying Property Can act as an emulsifier to stabilize emulsions
Biodegradability Biodegradable under certain conditions
Ionic Nature Anionic polymer
Packing & Storage
Packing Pharmaceutical - grade CMC sodium, 25 - kg bag for reliable chemical packaging.
Storage Pharmaceutical grade Sodium Carboxymethyl Cellulose (CMC) should be stored in a cool, dry place. Keep it away from direct sunlight and sources of heat to prevent degradation. Store in a well - sealed container to avoid moisture absorption, which could affect its quality. Ensure the storage area is clean to prevent contamination.
Shipping Pharmaceutical - grade Sodium Carboxymethyl Cellulose CMC is shipped in well - sealed containers. Packaging ensures protection from moisture and contaminants. It is transported via reliable freight services, following strict safety regulations for chemicals.
Free Quote

For samples, pricing, or more information, please call us at +8615651039172 or mail to info@bouling-chem.com.

We will respond to you as soon as possible.

Tel: +8615651039172

Email: info@bouling-chem.com

Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC
General Information
Historical Development
To taste the use of medicine, there is a thing called Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC. Its origin is also the first to be noticed by researchers, and it is expected to advance in medicine. In the past, all researchers have thought hard to explore its properties and study its uses. At first, it was only clear about its coarseness, but after years of study, it gradually came to be known that it can be used in medicine for bonding and thickening. Years have passed, and researchers have been unremitting. From the end of knowledge to the detailed understanding of its principles, there are many benefits in the preparation of medicine. The use of CMC, from shallow to deep, from simple to complex, with the progress of medicine, has become an indispensable state today, and it is essential for the achievements of the pharmaceutical industry.
Product Overview
In modern times, there is a material used in medicine, called pharmaceutical-grade sodium carboxymethyl cellulose CMC. This agent is also exquisite in making, and it is widely used. Its nature is mild, and it is not in harmony with various medicines, which can make the quality of the medicine uniform and increase its stability. Looking at its shape, it is often in the shape of powder, white in color and pure in quality. It dissolves in water, quickly and evenly, and can form a colloidal liquid with good viscosity. In the pharmaceutical industry, it is the first choice for blending agents and suspending agents. Or making pill powder, or making ointment soup, all rely on its strength, which can make the effect of medicine more, and those who use it are salty and good. It is actually a good material for pharmaceuticals, and it is great for medicine.
Physical & Chemical Properties
Taste the wonder of the drug, it is related to the physical properties and characteristics. In today's discussion of Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC, its quality is also, with specific physical and chemical properties. Looking at its shape, or in the form of powder, it is delicate and uniform. Its solubility is quite good, it can gradually melt in water and be in a uniform state, it can be a solution, and it is suitable for the preparation of various preparations. In terms of its viscosity, it is moderate and controllable. When the drug is formed, it can help the ingredients to bond and form a stable state, so that the preparation has a good shape and stability. And its chemical properties are relatively stable, it is not easy to react with common drug ingredients, and it can ensure the constant quality of the drug. It is an indispensable material in the process of pharmacy.
Technical Specifications & Labeling
Guanfu Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC, its technical specifications and identification (product parameters) are the key. For CMC, it is necessary to clarify its purity geometry, impurity content must be low, and it is suitable for medicinal use. Looking at its properties, it should be a uniform powder, pure color, and no variegated odor. And its solubility also needs to meet the standard. In a specific solvent, it is instant and the solution is clear, without the risk of precipitation. On the logo, the product name, specification, batch, production date and other information must be clear and accurate, which is the proof of quality, so that doctors and patients can use it with peace of mind, and it is also the basis for the orderly operation of the pharmaceutical industry.
Preparation Method
To prepare medicinal grade sodium carboxymethyl cellulose (CMC), the method is as follows: In terms of raw materials, choose refined cotton as the base material, with sodium hydroxide, monochloroacetic acid, etc. The preparation process is very critical. First, the refined cotton is reacted with sodium hydroxide to form alkali cellulose. This step requires temperature control and time. Then, the alkali cellulose reacts with monochloroacetic acid, and etherification is used to obtain CMC crude products. The reaction steps are rigorous. During alkalization, the concentration, dosage, reaction temperature and time of sodium hydroxide all affect the properties of the product. In the etherification stage, the amount of monochloroacetic acid and the reaction conditions are also important. Precise regulation is required to make the reaction sufficient and the product reaches the pharmaceutical standard. The purification mechanism is that the crude product is washed, filtered, and impurities are removed to obtain high-purity CMC. After drying, crushing and other treatments, the final pharmaceutical grade product is obtained to meet the strict requirements of the pharmaceutical field.
Chemical Reactions & Modifications
Since modern times, chemical refinement has been achieved. In Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC, the study of various chemical changes and modifications has gradually flourished. Looking at its chemical response, it has obvious effects in various fields. In pharmaceuticals, it can be used as a adhesive to firmly combine the components of the drug, which is caused by chemical interactions. As for modification, modified CMC can increase its solubility and stability. If its molecular structure is chemically adjusted, the change of carboxyl groups can change its hydrophilic and hydrophobic properties. This chemical change leads to the optimization of its performance, which is of great benefit to industry and medicine. Although the research road is long, the exploration of chemical response and modification will make CMC more suitable for the needs of the world, add brilliance to various industries, and promote its progress.
Synonyms & Product Names
Among the medicines, there is a thing called sodium carboxymethyl cellulose, its name is Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC. There are many aliases for this thing, or sodium carboxymethyl ether cellulose salt, or cellulose gum, etc. It is a medicinal grade sodium carboxymethyl cellulose with a wide range of uses. In the pharmaceutical industry, it can be used as a adhesive, a disintegrant, etc., to help pills form and drugs disintegrate. On the market, this drug name is often used in various products under different names. Its quality is excellent, and it is an indispensable raw material for pharmaceuticals. Many pharmacies use it to make good medicines, benefiting everyone. Therefore, although the names are different, they all refer to this Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC, which has significant efficacy and has extraordinary achievements in the field of medicine.
Safety & Operational Standards
Nowadays, there is Pharmaceutical Grade Sodium Carboxymethyl Cellulose (CMC), which is important for its safety and operating standards. This CMC is widely used in the pharmaceutical field. The most important thing for its safety is the selection of raw materials. It is necessary to choose pure, free and strictly tested raw materials to prevent the mixing of harmful impurities and endanger the quality of drugs and personal safety. When storing, it should be placed in a dry, cool and well-ventilated place. If the environment is humid, CMC is prone to moisture and agglomeration, which affects its performance and use. During access, keep the tool clean and avoid foreign matter incorporation. In terms of operation specifications, accurate measuring tools are required for weighing, which are accurately weighed according to the formula requirements. There is a slight deviation, or the properties of the drug may change. When dissolving, it is advisable to slowly add CMC to an appropriate amount of solvent, and stir at a uniform speed to promote uniform dispersion. If added too quickly or unevenly, it is easy to agglomerate and difficult to achieve a good dissolution effect. In addition, operators should wear clean work clothes, masks and gloves to prevent contamination of the product. After use, the utensils used must be cleaned in time and stored properly for next use. Only by strictly observing safety and operating standards can CMC play its due role in the pharmaceutical process and ensure the safety and quality of drugs.
Application Area
Pharmaceutical grade carboxymethyl cellulose sodium CMC has a wide range of applications. In the field of medicine, it can be used as a drug excipient to help the drug form a specific shape and ensure its stability. For example, when making tablets, it can adjust the disintegration rate of the drug and make the drug take effect in a timely manner. In the paste, it increases its viscosity, facilitates application and maintains quality. In the genus of food, it is used as a thickening and stabilizing agent. It makes beverages and dairy products uniform and not layered, and pastries have better texture. In the field of daily chemical, it is used for toothpaste to increase its consistency, making the paste easy to extrude and stable in shape; in skin care products, it adjusts texture and helps active ingredients disperse. The use of CMC is important in various fields, and it is actually a material with a wide range of functions.
Research & Development
Today, we have developed pharmaceutical-grade sodium carboxymethyl cellulose (CMC), which has a wide range of uses and has made great contributions to the field of medicine. At first, the preparation process was complicated and the output was limited. We worked hard day and night to improve the process and improve the purity and quality. After repeated tests, the reaction conditions and the ratio of raw materials were optimized. Today, the CMC produced is of high quality and can accurately meet the needs of pharmaceutical preparations. Looking at the past, many difficulties need to be broken, such as impurity removal and stability enhancement. However, with unremitting efforts, we can overcome them one by one. In the future, we still need to make great progress and expand its application in new drug delivery systems and other fields, so as to contribute to the development of medicine and promote the industry to new frontiers.
Toxicity Research
Since modern times, the pharmaceutical industry has flourished, and many drugs are related to people's health. There is now Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC, which is widely used in the pharmaceutical field. However, the investigation of its toxicity cannot be ignored. I have dedicated myself to studying in detail the characteristics, preparation methods and applications of CMC. Observe its effect in pharmaceuticals, either thickening or bonding. However, although it is widely used, the subtle changes in its toxicity may also affect the safety of medication. After repeated experiments, various animals were used as samples to observe the physiological changes of CMC after ingestion. Observe its diet, movement, organ characterization, etc., and record in detail. After long-term study, it is initially known that its toxicity is still minimal under conventional dosage, but the potential toxicity of excessive or long-term use still needs to be further investigated to ensure that the medication is foolproof.
Future Prospects
Guanfu Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC is a treasure in the pharmaceutical industry. It has many functions in the preparation of medicine, and can be used as adhesives, disintegrants, etc., to help the drug form and promote the efficacy of the drug. Looking forward to the future, the development of CMC has infinite potential. With the development of science and technology and the advancement of medicine, the requirements for its quality and performance must be increasingly stringent. The road of research and development should move towards high purity, high efficiency and safety. Or it can emerge in new drug delivery systems, adding a powerful tool for the treatment of difficult diseases. Or in the field of green pharmaceuticals, with its environmental protection characteristics, show your skills. In the future, CMC will surely be able to ride the east wind of science and technology to create new brilliance for the great cause of medicine and benefit the common people.
Frequently Asked Questions
Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC main application fields
Pharmaceutical grade sodium carboxymethyl cellulose (CMC) has a wide range of uses and is used in many fields such as medicine, food, daily chemicals, etc. In the field of medicine, its function is remarkable. It can be used as a tablet adhesive to make the drug powder tightly bound and firmly formed, ensuring that the tablet will not be loose during preparation and storage. Such as pill making, it can help the drug to form and improve the stability and quality of the pill. And in suspensions, CMC acts as a suspending agent to make the drug particles evenly dispersed without rapid sedimentation, ensuring the uniformity of drug efficacy. In external preparations such as ointments and creams, it can adjust the consistency of the preparation, making it comfortable to apply, easier to adhere to the skin or mucosal surface, and conducive to drug absorption. In the food industry, CMC is also an important additive. It is often used as a thickener to increase the viscosity of food, such as yogurt, jam, etc., to make the taste more mellow and delicate. In ice cream, it can prevent the formation of ice crystals, maintain uniform texture, and prolong shelf life. At the same time, it also has an emulsifying function to stabilize the oil-water system, such as in salad dressings, to avoid the separation of oil and water phases and ensure product quality. In the field of daily chemicals, CMC is also widely used. In toothpaste, it can control the rheological properties of the paste, make it extrude smoothly, and stabilize the paste composition to prevent delamination. In liquid detergents such as shampoo and body wash, as a thickener and foam stabilizer, it enhances the product experience, enhances foam stability, and makes cleaning more thorough. It can be seen that pharmaceutical grade sodium carboxymethyl cellulose (CMC) plays an indispensable role in the pharmaceutical, food, daily chemical and other industries, and is of great significance to improving product quality and performance.
Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC Compared to Other Similar Products
Pharmaceutical-grade sodium carboxymethyl cellulose (CMC) has significant advantages over other similar products. First of all, in terms of purity, pharmaceutical-grade CMC has undergone a rigorous purification process with very few impurities. Just like the ancient pure gold, it has been tempered for thousands of times to remove the voids and save the cyanine. Such high purity makes it possible to use it in the pharmaceutical field without introducing excess impurities to interfere with the efficacy of drugs and ensure the safety of medication. Furthermore, when it comes to stability, CMC can maintain good physical and chemical properties under different environmental conditions. Like a strong fortress, it is as safe as a mountain without wind or rain. Whether it is temperature changes or humidity fluctuations, it can maintain its own characteristics, providing strong support for the quality stability of the drug, ensuring that the quality of the drug is the same during storage and use. Solubility is also one of its highlights. Pharmaceutical-grade CMC can dissolve quickly and evenly in water, just like spring snow melting in a warm stream, smooth and natural. This feature is convenient for the preparation of pharmaceutical preparations, so that the active ingredients can be evenly dispersed, improving the uniformity and efficacy of the drug. And it has excellent thickening and emulsifying properties. Thickening, such as building embankments with gels, makes the drug system more stable; emulsification is like reconciling oil and water, so that insoluble components coexist harmoniously, thereby optimizing drug dosage forms, such as preparing creams, suspensions, etc., and improving patient medication compliance. And because of its good biocompatibility, the human body tolerates it well, and it is not easy to cause adverse reactions such as allergies. Just like the guest and host, it is harmonious and harmonious, and can be widely used in oral, external and other pharmaceutical dosage forms, providing a reliable choice of pharmaceutical excipients for the pharmaceutical industry.
Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC Quality Standards
Pharmaceutical - Grade Sodium Carboxymethyl Cellulose (CMC) is a commonly used excipient in the pharmaceutical field. Its Quality Standard is critical to the safety and efficacy of the drug. First, the appearance properties must be white to slightly yellow powder or particles, without visible impurities, uniform texture, this is the basic visual judgment standard, which is related to the intuitive quality of the product. Second, the degree of substitution is extremely important. The degree of substitution refers to the degree of substitution of hydroxyl groups in cellulose glucose units by carboxymethyl groups. The degree of substitution of pharmaceutical-grade CMC often needs to reach 0.6 - 0.95. The appropriate degree of substitution can affect the solubility, viscosity and stability of CMC. If the substitution is too low, the solubility of CMC in water is not good, and it cannot effectively exert its functions such as thickening and dispersing; if the substitution is too high, its stability may decrease. Third, viscosity is also a key indicator. According to different medicinal needs, the viscosity range varies greatly, and is generally measured in milliPa · s (mPa · s). For example, when used in oral preparations, low viscosity is often required to ensure the taste and fluidity of the preparation; when used in external preparations, such as ointments and gels, high viscosity may be required to maintain the stability of the formulation. Fourth, in terms of purity, the impurity content should be strictly controlled. Excessive impurities such as sodium chloride may affect the osmotic pressure of the drug, which in turn affects the absorption and distribution of the drug; heavy metals and microbial limits must also meet strict standards to prevent the introduction of harmful substances and endanger the health of patients. Fifth, the pH range usually needs to be maintained at 6.0-8.5. An appropriate pH value helps to ensure the stability of CMC in different drug systems and avoid abnormal pH value affecting drug activity or causing adverse reactions.
Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC During Storage and Transportation
Pharmaceutical grade sodium carboxymethyl cellulose (CMC) requires many matters to be paid attention to during storage and transportation. Its nature prefers dryness, and if placed in a humid place, it is very easy to absorb moisture. Once it absorbs moisture, it will not only cause poor fluidity, but may also breed microorganisms and damage quality. Therefore, when storing, it must be selected in a dry, ventilated and humidity-controlled place. The relative humidity should be controlled within a specific range, generally speaking, no more than 60%. Temperature is also crucial. Excessive temperature may cause it to degrade, and too low temperature may affect its solubility and performance. Usually the suitable storage temperature is between 5 ° C and 35 ° C. Do not expose the drug to extreme high or low temperature environments. When transporting, the packaging must be intact. Due to its delicate texture, if the packaging is damaged, it is easy to cause powder leakage during handling, which not only wastes materials, but also pollutes the surrounding environment. And in the transportation vehicle, it should also be kept dry and at a suitable temperature to avoid rain and sun exposure. In addition, pharmaceutical-grade CMC is a pharmaceutical excipient, which is related to drug safety. The place of storage and transportation must not be stored and transported with toxic, harmful, and odorous substances to prevent cross-contamination. The transportation process should also be as smooth as possible to avoid violent vibration and collision, which will cause damage to the packaging or change the quality. Therefore, it is necessary to ensure that pharmaceutical-grade sodium carboxymethyl cellulose (CMC) maintains good quality and performance during storage and transportation, providing reliable protection for pharmaceutical use.
Pharmaceutical Grade Sodium CarboxyMethyl Cellulose CMC Price Range
Pharmaceutical Grade Sodium Carboxymethyl Cellulose (CMC) is a pharmaceutical grade sodium carboxymethyl cellulose. Its price range often varies due to various factors. Looking at the situation of the market in the past, the price of this drug may vary depending on the quality, the distance of the place of origin, and the amount of supply and demand. If the quality is high, it comes from a good place, and there are many people in the market who want it, but there are few people who supply it, the price will be high; on the contrary, if the quality is slightly inferior, the place of origin is nearby, and the market oversupply, the price may be slightly lower. Generally speaking, the price range is between tens of yuan and hundreds of yuan per kilogram. For those of ordinary quality, the price per kilogram or tens of yuan; if it is a fine and special product with excellent quality, the price may be close to a hundred yuan or even a few hundred yuan per kilogram. However, this is only an approximate number, and the actual price often changes with the change of the market. Market prices are like changes in the wind and clouds, or vary from time to time or events. Therefore, if you want to know the exact price, you should carefully observe the situation of the current market change, and consult the merchants and brokers before you can get a close number.