Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC main application fields
Pharmaceutical grade sodium carboxymethyl cellulose (CMC) has a wide range of uses and is used in many fields such as medicine, food, daily chemicals, etc.
In the field of medicine, its function is remarkable. It can be used as a tablet adhesive to make the drug powder tightly bound and firmly formed, ensuring that the tablet will not be loose during preparation and storage. Such as pill making, it can help the drug to form and improve the stability and quality of the pill. And in suspensions, CMC acts as a suspending agent to make the drug particles evenly dispersed without rapid sedimentation, ensuring the uniformity of drug efficacy. In external preparations such as ointments and creams, it can adjust the consistency of the preparation, making it comfortable to apply, easier to adhere to the skin or mucosal surface, and conducive to drug absorption.
In the food industry, CMC is also an important additive. It is often used as a thickener to increase the viscosity of food, such as yogurt, jam, etc., to make the taste more mellow and delicate. In ice cream, it can prevent the formation of ice crystals, maintain uniform texture, and prolong shelf life. At the same time, it also has an emulsifying function to stabilize the oil-water system, such as in salad dressings, to avoid the separation of oil and water phases and ensure product quality.
In the field of daily chemicals, CMC is also widely used. In toothpaste, it can control the rheological properties of the paste, make it extrude smoothly, and stabilize the paste composition to prevent delamination. In liquid detergents such as shampoo and body wash, as a thickener and foam stabilizer, it enhances the product experience, enhances foam stability, and makes cleaning more thorough.
It can be seen that pharmaceutical grade sodium carboxymethyl cellulose (CMC) plays an indispensable role in the pharmaceutical, food, daily chemical and other industries, and is of great significance to improving product quality and performance.
Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC Compared to Other Similar Products
Pharmaceutical-grade sodium carboxymethyl cellulose (CMC) has significant advantages over other similar products.
First of all, in terms of purity, pharmaceutical-grade CMC has undergone a rigorous purification process with very few impurities. Just like the ancient pure gold, it has been tempered for thousands of times to remove the voids and save the cyanine. Such high purity makes it possible to use it in the pharmaceutical field without introducing excess impurities to interfere with the efficacy of drugs and ensure the safety of medication.
Furthermore, when it comes to stability, CMC can maintain good physical and chemical properties under different environmental conditions. Like a strong fortress, it is as safe as a mountain without wind or rain. Whether it is temperature changes or humidity fluctuations, it can maintain its own characteristics, providing strong support for the quality stability of the drug, ensuring that the quality of the drug is the same during storage and use.
Solubility is also one of its highlights. Pharmaceutical-grade CMC can dissolve quickly and evenly in water, just like spring snow melting in a warm stream, smooth and natural. This feature is convenient for the preparation of pharmaceutical preparations, so that the active ingredients can be evenly dispersed, improving the uniformity and efficacy of the drug.
And it has excellent thickening and emulsifying properties. Thickening, such as building embankments with gels, makes the drug system more stable; emulsification is like reconciling oil and water, so that insoluble components coexist harmoniously, thereby optimizing drug dosage forms, such as preparing creams, suspensions, etc., and improving patient medication compliance.
And because of its good biocompatibility, the human body tolerates it well, and it is not easy to cause adverse reactions such as allergies. Just like the guest and host, it is harmonious and harmonious, and can be widely used in oral, external and other pharmaceutical dosage forms, providing a reliable choice of pharmaceutical excipients for the pharmaceutical industry.
Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC Quality Standards
Pharmaceutical - Grade Sodium Carboxymethyl Cellulose (CMC) is a commonly used excipient in the pharmaceutical field. Its Quality Standard is critical to the safety and efficacy of the drug.
First, the appearance properties must be white to slightly yellow powder or particles, without visible impurities, uniform texture, this is the basic visual judgment standard, which is related to the intuitive quality of the product.
Second, the degree of substitution is extremely important. The degree of substitution refers to the degree of substitution of hydroxyl groups in cellulose glucose units by carboxymethyl groups. The degree of substitution of pharmaceutical-grade CMC often needs to reach 0.6 - 0.95. The appropriate degree of substitution can affect the solubility, viscosity and stability of CMC. If the substitution is too low, the solubility of CMC in water is not good, and it cannot effectively exert its functions such as thickening and dispersing; if the substitution is too high, its stability may decrease.
Third, viscosity is also a key indicator. According to different medicinal needs, the viscosity range varies greatly, and is generally measured in milliPa · s (mPa · s). For example, when used in oral preparations, low viscosity is often required to ensure the taste and fluidity of the preparation; when used in external preparations, such as ointments and gels, high viscosity may be required to maintain the stability of the formulation.
Fourth, in terms of purity, the impurity content should be strictly controlled. Excessive impurities such as sodium chloride may affect the osmotic pressure of the drug, which in turn affects the absorption and distribution of the drug; heavy metals and microbial limits must also meet strict standards to prevent the introduction of harmful substances and endanger the health of patients.
Fifth, the pH range usually needs to be maintained at 6.0-8.5. An appropriate pH value helps to ensure the stability of CMC in different drug systems and avoid abnormal pH value affecting drug activity or causing adverse reactions.
Pharmaceutical Grade Sodium Carboxymethyl Cellulose CMC During Storage and Transportation
Pharmaceutical grade sodium carboxymethyl cellulose (CMC) requires many matters to be paid attention to during storage and transportation.
Its nature prefers dryness, and if placed in a humid place, it is very easy to absorb moisture. Once it absorbs moisture, it will not only cause poor fluidity, but may also breed microorganisms and damage quality. Therefore, when storing, it must be selected in a dry, ventilated and humidity-controlled place. The relative humidity should be controlled within a specific range, generally speaking, no more than 60%.
Temperature is also crucial. Excessive temperature may cause it to degrade, and too low temperature may affect its solubility and performance. Usually the suitable storage temperature is between 5 ° C and 35 ° C. Do not expose the drug to extreme high or low temperature environments.
When transporting, the packaging must be intact. Due to its delicate texture, if the packaging is damaged, it is easy to cause powder leakage during handling, which not only wastes materials, but also pollutes the surrounding environment. And in the transportation vehicle, it should also be kept dry and at a suitable temperature to avoid rain and sun exposure.
In addition, pharmaceutical-grade CMC is a pharmaceutical excipient, which is related to drug safety. The place of storage and transportation must not be stored and transported with toxic, harmful, and odorous substances to prevent cross-contamination. The transportation process should also be as smooth as possible to avoid violent vibration and collision, which will cause damage to the packaging or change the quality. Therefore, it is necessary to ensure that pharmaceutical-grade sodium carboxymethyl cellulose (CMC) maintains good quality and performance during storage and transportation, providing reliable protection for pharmaceutical use.
Pharmaceutical Grade Sodium CarboxyMethyl Cellulose CMC Price Range
Pharmaceutical Grade Sodium Carboxymethyl Cellulose (CMC) is a pharmaceutical grade sodium carboxymethyl cellulose. Its price range often varies due to various factors.
Looking at the situation of the market in the past, the price of this drug may vary depending on the quality, the distance of the place of origin, and the amount of supply and demand. If the quality is high, it comes from a good place, and there are many people in the market who want it, but there are few people who supply it, the price will be high; on the contrary, if the quality is slightly inferior, the place of origin is nearby, and the market oversupply, the price may be slightly lower.
Generally speaking, the price range is between tens of yuan and hundreds of yuan per kilogram. For those of ordinary quality, the price per kilogram or tens of yuan; if it is a fine and special product with excellent quality, the price may be close to a hundred yuan or even a few hundred yuan per kilogram. However, this is only an approximate number, and the actual price often changes with the change of the market. Market prices are like changes in the wind and clouds, or vary from time to time or events. Therefore, if you want to know the exact price, you should carefully observe the situation of the current market change, and consult the merchants and brokers before you can get a close number.